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The anthelmintic drug flubendazole induces cell apoptosis and inhibits NF-κB signaling in esophageal squamous cell carcinoma

BACKGROUND AND OBJECTIVES: The nuclear factor kappa B (NF-κB) signaling is activated in esophageal squamous cell carcinoma (ESCC) and can be used as a potential target for anti-ESCC drug discovery. In this study, we aimed to investigate the function of flubendazole as a novel NF-κB inhibitor in ESCC...

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Detalles Bibliográficos
Autores principales:	Tao, Jiali, Zhao, Hongmei, Xie, Xiaochen, Luo, Man, Gao, Zhiwei, Sun, Hong, Huang, Ziming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331185/ https://www.ncbi.nlm.nih.gov/pubmed/30666126 http://dx.doi.org/10.2147/OTT.S193206

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