HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

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Eliciting HIV-1-specific broadly neutralizing antibodies (bNAbs) remains a challenge for vaccine development, and the potential of passively delivered bNAbs for prophylaxis and therapeutics is being explored. We used neutralization data from four large virus panels to comprehensively map viral signa...

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Detalles Bibliográficos
Autores principales: Bricault, Christine A., Yusim, Karina, Seaman, Michael S., Yoon, Hyejin, Theiler, James, Giorgi, Elena E., Wagh, Kshitij, Theiler, Maxwell, Hraber, Peter, Macke, Jennifer P., Kreider, Edward F., Learn, Gerald H., Hahn, Beatrice H., Scheid, Johannes F., Kovacs, James M., Shields, Jennifer L., Lavine, Christy L., Ghantous, Fadi, Rist, Michael, Bayne, Madeleine G., Neubauer, George H., McMahan, Katherine, Peng, Hanqin, Chéneau, Coraline, Jones, Jennifer J., Zeng, Jie, Ochsenbauer, Christina, Nkolola, Joseph P., Stephenson, Kathryn E., Chen, Bing, Gnanakaran, S., Bonsignori, Mattia, Williams, LaTonya D., Haynes, Barton F., Doria-Rose, Nicole, Mascola, John R., Montefiori, David C., Barouch, Dan H., Korber, Bette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331341/
https://www.ncbi.nlm.nih.gov/pubmed/30629920
http://dx.doi.org/10.1016/j.chom.2018.12.001

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