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Functional Blockade of Small GTPase RAN Inhibits Glioblastoma Cell Viability

Glioblastoma, the most common malignant tumor in the brain, lacks effective treatments and is currently incurable. To identify novel drug targets for this deadly cancer, the publicly available results of RNA interference screens from the Project Achilles database were analyzed. Ten candidate genes w...

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Detalles Bibliográficos
Autores principales: Sheng, Kevin L., Pridham, Kevin J., Sheng, Zhi, Lamouille, Samy, Varghese, Robin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331428/
https://www.ncbi.nlm.nih.gov/pubmed/30671385
http://dx.doi.org/10.3389/fonc.2018.00662