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Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses
Mitochondria modulate cellular calcium homeostasis by the combined action of the mitochondrial calcium uniporter (MCU), a selective calcium entry channel, and the sodium calcium exchanger (NCLX), which extrudes calcium from mitochondria. In this study, we investigated MCU and NCLX in noise-induced h...
Autores principales: | Wang, Xianren, Zhu, Yuanping, Long, Haishan, Pan, Song, Xiong, Hao, Fang, Qiaojun, Hill, Kayla, Lai, Ruosha, Yuan, Hu, Sha, Su-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331433/ https://www.ncbi.nlm.nih.gov/pubmed/30670946 http://dx.doi.org/10.3389/fnmol.2018.00469 |
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