Cargando…
IRF and STAT Transcription Factors - From Basic Biology to Roles in Infection, Protective Immunity, and Primary Immunodeficiencies
The induction and action of type I interferon (IFN) is of fundamental importance in human immune defenses toward microbial pathogens, particularly viruses. Basic discoveries within the molecular and cellular signaling pathways regulating type I IFN induction and downstream actions have shown the ess...
Autor principal: | Mogensen, Trine H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331453/ https://www.ncbi.nlm.nih.gov/pubmed/30671054 http://dx.doi.org/10.3389/fimmu.2018.03047 |
Ejemplares similares
-
Editorial: STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets
por: Lee, Chien-Kuo, et al.
Publicado: (2019) -
The Molecular Basis of Viral Inhibition of IRF- and STAT-Dependent Immune Responses
por: Chiang, Hao-Sen, et al.
Publicado: (2019) -
IRF7: role and regulation in immunity and autoimmunity
por: Ma, Wei, et al.
Publicado: (2023) -
Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
por: Platanitis, Ekaterini, et al.
Publicado: (2018) -
SPOP targets the immune transcription factor IRF1 for proteasomal degradation
por: Schwartz, Irene, et al.
Publicado: (2023)