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Dimethyl fumarate treatment induces lipid metabolism alterations that are linked to immunological changes

OBJECTIVE: Identify metabolic changes produced by dimethyl fumarate (DMF) treatment and link them to immunological effects. METHODS: We enrolled 18 MS patients and obtained blood prior to DMF and 6 months postinitiation. We also enrolled 18 healthy controls for comparison. We performed global metabo...

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Detalles Bibliográficos
Autores principales: Bhargava, Pavan, Fitzgerald, Kathryn C., Venkata, Swarajya L. V., Smith, Matthew D., Kornberg, Michael D., Mowry, Ellen M., Haughey, Norman J., Calabresi, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331509/
https://www.ncbi.nlm.nih.gov/pubmed/30656182
http://dx.doi.org/10.1002/acn3.676