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Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses

Coxsackievirus A10 (CV-A10) belongs to the Enterovirus species A and is a causative agent of hand, foot, and mouth disease. Here we present cryo-EM structures of CV-A10 mature virion and native empty particle (NEP) at 2.84 and 3.12 Å, respectively. Our CV-A10 mature virion structure reveals a densit...

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Detalles Bibliográficos
Autores principales:	Chen, Jinhuan, Ye, Xiaohua, Zhang, Xue-Yang, Zhu, Zhengdan, Zhang, Xiang, Xu, Zhijian, Ding, Zhanyu, Zou, Gang, Liu, Qingwei, Kong, Liangliang, Jiang, Wen, Zhu, Weiliang, Cong, Yao, Huang, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331555/ https://www.ncbi.nlm.nih.gov/pubmed/30652025 http://dx.doi.org/10.1038/s41421-018-0073-7

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