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Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress

We developed a high-throughput mass spectrometry–based method to simultaneously quantify numerous small-molecule thiols and disulfides in blood plasma. Application of this assay to analyze plasma from patients with known oxidative stress (sickle cell disease and sepsis) and from a patient with sickl...

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Detalles Bibliográficos
Autores principales:	Fu, Xiaoyun, Cate, Shelby A., Dominguez, Melissa, Osborn, Warren, Özpolat, Tahsin, Konkle, Barbara A., Chen, Junmei, López, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331564/ https://www.ncbi.nlm.nih.gov/pubmed/30643157 http://dx.doi.org/10.1038/s41598-018-35566-2

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