Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

Bacterial mutations predisposing pneumococcus to causing meningitis, a more severe form of invasive pneumococcal disease (IPD), are largely unknown. Knowledge of such mutations may improve our understanding of pathogenesis and inform preventive strategies. Here we report a pneumococcal pbp1b gene mu...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Metcalf, Benjamin J., Chochua, Sopio, Li, Zhongya, Walker, Hollis, Tran, Theresa, Hawkins, Paulina A., Gierke, Ryan, Pilishvili, Tamara, McGee, Lesley, Beall, Bernard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331587/
https://www.ncbi.nlm.nih.gov/pubmed/30643125
http://dx.doi.org/10.1038/s41467-018-07997-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331587/
https://www.ncbi.nlm.nih.gov/pubmed/30643125
http://dx.doi.org/10.1038/s41467-018-07997-y

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