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Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis
Bacterial mutations predisposing pneumococcus to causing meningitis, a more severe form of invasive pneumococcal disease (IPD), are largely unknown. Knowledge of such mutations may improve our understanding of pathogenesis and inform preventive strategies. Here we report a pneumococcal pbp1b gene mu...
Autores principales: | Li, Yuan, Metcalf, Benjamin J., Chochua, Sopio, Li, Zhongya, Walker, Hollis, Tran, Theresa, Hawkins, Paulina A., Gierke, Ryan, Pilishvili, Tamara, McGee, Lesley, Beall, Bernard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331587/ https://www.ncbi.nlm.nih.gov/pubmed/30643125 http://dx.doi.org/10.1038/s41467-018-07997-y |
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