A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium

Salmonella Typhimurium (S. Tm) establishes systemic infection in susceptible hosts by evading the innate immune response and replicating within host phagocytes. Here, we sought to identify inhibitors of intracellular S. Tm replication by conducting parallel chemical screens against S. Tm growing in...

Descripción completa

Detalles Bibliográficos
Autores principales: Ellis, Michael J., Tsai, Caressa N., Johnson, Jarrod W., French, Shawn, Elhenawy, Wael, Porwollik, Steffen, Andrews-Polymenis, Helene, McClelland, Michael, Magolan, Jakob, Coombes, Brian K., Brown, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331611/
https://www.ncbi.nlm.nih.gov/pubmed/30643129
http://dx.doi.org/10.1038/s41467-018-08190-x

Ejemplares similares

Ejemplares similares