Cargando…

Systems Genomics of Thigh Adipose Tissue From Asian Indian Type-2 Diabetics Revealed Distinct Protein Interaction Hubs

We performed a systematic analysis of genes implicated in thigh subcutaneous adipose tissue of Asian Indian Type 2 Diabetes Mellitus (AIT2DM) and created a phenome-interactome network. This analysis was performed on 60 subjects specific to limb thigh fat by integrating phenotypic traits and similari...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tiwari, Pradeep, Saxena, Aditya, Gupta, Nidhi, Medicherla, Krishna Mohan, Suravajhala, Prashanth, Mathur, Sandeep Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331691/ https://www.ncbi.nlm.nih.gov/pubmed/30671081 http://dx.doi.org/10.3389/fgene.2018.00679

Ejemplares similares

Transcriptome profiling reveals association of peripheral adipose tissue pathology with type-2 diabetes in Asian Indians
por: Saxena, Aditya, et al.
Publicado: (2019)

Genetics of Lipodystrophy: Can It Help in Understanding the Pathophysiology of Metabolic Syndrome?
por: Mathur, Sandeep Kumar, et al.
Publicado: (2018)

Application of Chromosomal Microarray for Evaluation of Idiopathic Short Stature in Asian Indian Children: A Pilot Study
por: Singh, Hema, et al.
Publicado: (2018)

SUN-LB106 The Transcriptomic Evidences on Role of Abdominal Visceral vs. Subcutaneous Adipose Tissue in the Pathophysiology of Diabetes in Asian Indian Indicates the Involvement of Both
por: Mathur, Sandeep Kumar, et al.
Publicado: (2020)

Is Pouch Specific to Colon and Not Ileum?
por: Gupta, Sonal, et al.
Publicado: (2019)

The common pathophysiologic threads between Asian Indian diabetic’s ‘Thin Fat Phenotype’ and partial lipodystrophy: the peripheral adipose tissue transcriptomic evidences
por: Saxena, Aditya, et al.
Publicado: (2020)

Lnc-EPB41-Protein Interactions Associated with Congenital Pouch Colon
por: Gupta, Sonal, et al.
Publicado: (2018)

The Transcriptomic Evidence on the Role of Abdominal Visceral vs. Subcutaneous Adipose Tissue in the Pathophysiology of Diabetes in Asian Indians Indicates the Involvement of Both
por: Kumar, Anshul, et al.
Publicado: (2020)

Whole transcriptome RNA-seq reveals key regulatory factors involved in type 2 diabetes pathology in peripheral fat of Asian Indians
por: Saxena, Aditya, et al.
Publicado: (2021)

A Pilot Study on the Whole Exome Sequencing of Prostate Cancer in the Indian Phenotype Reveals Distinct Polymorphisms
por: Gupta, Ayam, et al.
Publicado: (2020)

Whole exome sequencing reveals rare variants linked to congenital pouch colon
por: Mathur, Praveen, et al.
Publicado: (2018)

Author Correction: Whole exome sequencing reveals rare variants linked to congenital pouch colon
por: Mathur, Praveen, et al.
Publicado: (2018)

Insulin Resistance Shows Stronger Correlation With Ectopic Liver Fat Instead of Visceral Fat in Asian Indians
por: Garg, Umesh Kumar, et al.
Publicado: (2021)

Whole Exome-Trio Analysis Reveals Rare Variants Associated with Congenital Pouch Colon
por: Gupta, Sonal, et al.
Publicado: (2023)

Towards Understanding the Key Signature Pathways Associated from Differentially Expressed Gene Analysis in an Indian Prostate Cancer Cohort
por: Shukla, Nidhi, et al.
Publicado: (2023)

Diabetes mellitus susceptibility with varied diseased phenotypes and its comparison with phenome interactome networks
por: Rout, Madhusmita, et al.
Publicado: (2022)

Draft Genome Sequence of a Fungus (Fusarium tricinctum) Cultured from a Monoisolate Native to the Himalayas
por: Meena, Narendra, et al.
Publicado: (2018)

Draft Genome Sequence of the Plant Growth-Promoting Rhizobacterium Pseudomonas protegens Strain BNJ-SS-45, Isolated from Rhizosphere Soil of Wheat (Triticum aestivum)
por: Bajpai, Apekcha, et al.
Publicado: (2018)

Diabetes and Insulin Resistance Show Association With Femoral Instead of Abdominal Adipocyte Size in Asian Indians
por: Sahlot, Rahul, et al.
Publicado: (2021)

Editorial: Annotation and curation of uncharacterized proteins: systems biology approaches
por: Suravajhala, Prashanth, et al.
Publicado: (2015)

Editorial: Bioinformatics and the Translation of Data-Driven Discoveries
por: Khan, Asif M., et al.
Publicado: (2022)

Potential role of lncRNA cyp2c91–protein interactions on diseases of the immune system
por: Suravajhala, Prashanth, et al.
Publicado: (2015)

Editorial: Integrated systems genomic approaches for characterizing uncharacterized proteins
por: Valadi, Jayaraman, et al.
Publicado: (2022)

Machine Learning Model Based on Insulin Resistance Metagenes Underpins Genetic Basis of Type 2 Diabetes
por: Saxena, Aditya, et al.
Publicado: (2023)

Data Mining and Pattern Recognition Models for Identifying Inherited Diseases: Challenges and Implications
por: Iddamalgoda, Lahiru, et al.
Publicado: (2016)

Inferring bona fide Differentially Expressed Genes and Their Variants Associated with Vitamin K Deficiency Using a Systems Genetics Approach
por: Rajagopal, Shalini, et al.
Publicado: (2022)

BBBomics-Human Blood Brain Barrier Transcriptomics Hub
por: Kalari, Krishna R., et al.
Publicado: (2016)

In Silico Characterization of Uncharacterized Proteins From Multiple Strains of Clostridium Difficile
por: Abbasi, Bilal Ahmed, et al.
Publicado: (2022)

Genetic Markers for Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis in the Asian Indian Population: Implications on Prevention
por: Shanbhag, Swapna S., et al.
Publicado: (2021)

Copy Number Variations Are More Frequent on Chromosome 14 as Compared to X Chromosome in Suspected Turner Syndrome Girls - A Chromosomal Microarray Analysis
por: Purwar, Naincy, et al.
Publicado: (2021)

Relationship of Adipocyte Size with Adiposity and Metabolic Risk Factors in Asian Indians
por: Meena, Ved Prakash, et al.
Publicado: (2014)

Editorial: Linkage between membrane composition, cellular functions and membrane-mediated stress
por: Saha, Pradipta, et al.
Publicado: (2023)

Identification of Hub Genes With Differential Correlations in Sepsis
por: Sheng, Lulu, et al.
Publicado: (2022)

Analysis of Hub Genes Involved in Distinction Between Aged and Fetal Bone Marrow Mesenchymal Stem Cells by Robust Rank Aggregation and Multiple Functional Annotation Methods
por: Liu, Xiaoyao, et al.
Publicado: (2020)

Indian Red Jungle fowl reveals a genetic relationship with South East Asian Red Jungle fowl and Indian native chicken breeds as evidenced through whole mitochondrial genome sequences
por: Kanakachari, M., et al.
Publicado: (2023)

Identification of Immune-Related Hub Genes in Parkinson’s Disease
por: Chen, Lin, et al.
Publicado: (2022)

Waist–thigh Ratio: A Surrogate Marker for Type 2 Diabetes Mellitus in Asian North Indian Patients
por: Kumar, Shivanjali, et al.
Publicado: (2018)

Identification of Hub Genes and Immune Infiltration in Psoriasis by Bioinformatics Method
por: Su, Wenxing, et al.
Publicado: (2021)

Identification of susceptibility modules and hub genes of osteoarthritis by WGCNA analysis
por: Wang, Yanchao, et al.
Publicado: (2022)

Identification of the cuproptosis-related hub genes and therapeutic agents for sarcopenia
por: Zhu, Yingqian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gi5cf4a5d0qcf9cmsdke6j371t