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Identifying genetic markers associated with susceptibility to cardiovascular diseases
The development of cardiovascular diseases (CVDs) is due to a complex interaction between the genome and the environment. Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcom...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331704/ https://www.ncbi.nlm.nih.gov/pubmed/30652019 http://dx.doi.org/10.4155/fsoa-2018-0031 |
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author | Shukla, Hitesh Mason, Jessica Louise Sabyah, Abdullah |
author_facet | Shukla, Hitesh Mason, Jessica Louise Sabyah, Abdullah |
author_sort | Shukla, Hitesh |
collection | PubMed |
description | The development of cardiovascular diseases (CVDs) is due to a complex interaction between the genome and the environment. Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcome for the patient. As genome technologies evolve, genotyping of individuals could be available to all patients using a simple saliva test. Large-scale genome-wide association studies and meta analyses have provided powerful insights into polymorphisms that may be predictive of disease and an individual's response to certain nutrients, but moving forward it is imperative that these insights can be applied in the medical setting to reduce the incidence and mortality of CVDs. |
format | Online Article Text |
id | pubmed-6331704 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Future Science Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-63317042019-01-16 Identifying genetic markers associated with susceptibility to cardiovascular diseases Shukla, Hitesh Mason, Jessica Louise Sabyah, Abdullah Future Sci OA Review The development of cardiovascular diseases (CVDs) is due to a complex interaction between the genome and the environment. Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcome for the patient. As genome technologies evolve, genotyping of individuals could be available to all patients using a simple saliva test. Large-scale genome-wide association studies and meta analyses have provided powerful insights into polymorphisms that may be predictive of disease and an individual's response to certain nutrients, but moving forward it is imperative that these insights can be applied in the medical setting to reduce the incidence and mortality of CVDs. Future Science Ltd 2018-10-26 /pmc/articles/PMC6331704/ /pubmed/30652019 http://dx.doi.org/10.4155/fsoa-2018-0031 Text en © 2018 Rightangled Ltd This work is licensed under a Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Review Shukla, Hitesh Mason, Jessica Louise Sabyah, Abdullah Identifying genetic markers associated with susceptibility to cardiovascular diseases |
title | Identifying genetic markers associated with susceptibility to cardiovascular diseases |
title_full | Identifying genetic markers associated with susceptibility to cardiovascular diseases |
title_fullStr | Identifying genetic markers associated with susceptibility to cardiovascular diseases |
title_full_unstemmed | Identifying genetic markers associated with susceptibility to cardiovascular diseases |
title_short | Identifying genetic markers associated with susceptibility to cardiovascular diseases |
title_sort | identifying genetic markers associated with susceptibility to cardiovascular diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331704/ https://www.ncbi.nlm.nih.gov/pubmed/30652019 http://dx.doi.org/10.4155/fsoa-2018-0031 |
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