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Identifying genetic markers associated with susceptibility to cardiovascular diseases

The development of cardiovascular diseases (CVDs) is due to a complex interaction between the genome and the environment. Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcom...

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Detalles Bibliográficos
Autores principales: Shukla, Hitesh, Mason, Jessica Louise, Sabyah, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331704/
https://www.ncbi.nlm.nih.gov/pubmed/30652019
http://dx.doi.org/10.4155/fsoa-2018-0031
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author Shukla, Hitesh
Mason, Jessica Louise
Sabyah, Abdullah
author_facet Shukla, Hitesh
Mason, Jessica Louise
Sabyah, Abdullah
author_sort Shukla, Hitesh
collection PubMed
description The development of cardiovascular diseases (CVDs) is due to a complex interaction between the genome and the environment. Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcome for the patient. As genome technologies evolve, genotyping of individuals could be available to all patients using a simple saliva test. Large-scale genome-wide association studies and meta analyses have provided powerful insights into polymorphisms that may be predictive of disease and an individual's response to certain nutrients, but moving forward it is imperative that these insights can be applied in the medical setting to reduce the incidence and mortality of CVDs.
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spelling pubmed-63317042019-01-16 Identifying genetic markers associated with susceptibility to cardiovascular diseases Shukla, Hitesh Mason, Jessica Louise Sabyah, Abdullah Future Sci OA Review The development of cardiovascular diseases (CVDs) is due to a complex interaction between the genome and the environment. Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcome for the patient. As genome technologies evolve, genotyping of individuals could be available to all patients using a simple saliva test. Large-scale genome-wide association studies and meta analyses have provided powerful insights into polymorphisms that may be predictive of disease and an individual's response to certain nutrients, but moving forward it is imperative that these insights can be applied in the medical setting to reduce the incidence and mortality of CVDs. Future Science Ltd 2018-10-26 /pmc/articles/PMC6331704/ /pubmed/30652019 http://dx.doi.org/10.4155/fsoa-2018-0031 Text en © 2018 Rightangled Ltd This work is licensed under a Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Review
Shukla, Hitesh
Mason, Jessica Louise
Sabyah, Abdullah
Identifying genetic markers associated with susceptibility to cardiovascular diseases
title Identifying genetic markers associated with susceptibility to cardiovascular diseases
title_full Identifying genetic markers associated with susceptibility to cardiovascular diseases
title_fullStr Identifying genetic markers associated with susceptibility to cardiovascular diseases
title_full_unstemmed Identifying genetic markers associated with susceptibility to cardiovascular diseases
title_short Identifying genetic markers associated with susceptibility to cardiovascular diseases
title_sort identifying genetic markers associated with susceptibility to cardiovascular diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331704/
https://www.ncbi.nlm.nih.gov/pubmed/30652019
http://dx.doi.org/10.4155/fsoa-2018-0031
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