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Anti-Lymphoma Efficacy Comparison of Anti-CD20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates

Here we describe the synthesis and biological properties of two types of star-shaped polymer-doxorubicin conjugates: non-targeted conjugate prepared as long-circulating high-molecular-weight (HMW) polymer prodrugs with a dendrimer core and a targeted conjugate with the anti-CD20 monoclonal antibody...

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Detalles Bibliográficos
Autores principales:	Lidický, Ondřej, Janoušková, Olga, Strohalm, Jiří, Alam, Mahmudul, Klener, Pavel, Etrych, Tomáš
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331818/ https://www.ncbi.nlm.nih.gov/pubmed/26556320 http://dx.doi.org/10.3390/molecules201119664

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