Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate

3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Dahye, Park, Sunhwa, Yu, Yoseb, Shin, Kye Jung, Seo, Jae Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331821/
https://www.ncbi.nlm.nih.gov/pubmed/26247925
http://dx.doi.org/10.3390/molecules200814022
_version_ 1783387205726633984
author Lee, Dahye
Park, Sunhwa
Yu, Yoseb
Shin, Kye Jung
Seo, Jae Hong
author_facet Lee, Dahye
Park, Sunhwa
Yu, Yoseb
Shin, Kye Jung
Seo, Jae Hong
author_sort Lee, Dahye
collection PubMed
description 3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity.
format Online
Article
Text
id pubmed-6331821
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-63318212019-01-24 Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate Lee, Dahye Park, Sunhwa Yu, Yoseb Shin, Kye Jung Seo, Jae Hong Molecules Article 3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity. MDPI 2015-08-03 /pmc/articles/PMC6331821/ /pubmed/26247925 http://dx.doi.org/10.3390/molecules200814022 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Dahye
Park, Sunhwa
Yu, Yoseb
Shin, Kye Jung
Seo, Jae Hong
Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
title Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
title_full Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
title_fullStr Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
title_full_unstemmed Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
title_short Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
title_sort palladium-catalyzed one-pot approach to 3-(diarylmethylene)oxindoles from propiolamidoaryl triflate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331821/
https://www.ncbi.nlm.nih.gov/pubmed/26247925
http://dx.doi.org/10.3390/molecules200814022
work_keys_str_mv AT leedahye palladiumcatalyzedonepotapproachto3diarylmethyleneoxindolesfrompropiolamidoaryltriflate
AT parksunhwa palladiumcatalyzedonepotapproachto3diarylmethyleneoxindolesfrompropiolamidoaryltriflate
AT yuyoseb palladiumcatalyzedonepotapproachto3diarylmethyleneoxindolesfrompropiolamidoaryltriflate
AT shinkyejung palladiumcatalyzedonepotapproachto3diarylmethyleneoxindolesfrompropiolamidoaryltriflate
AT seojaehong palladiumcatalyzedonepotapproachto3diarylmethyleneoxindolesfrompropiolamidoaryltriflate

Ejemplares similares