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New Diethyl Ammonium Salt of Thiobarbituric Acid Derivative: Synthesis, Molecular Structure Investigations and Docking Studies

The synthesis of the new diethyl ammonium salt of diethylammonium(E)-5-(1,5-bis(4-fluorophenyl)-3-oxopent-4-en-1-yl)-1,3-diethyl-4,6-dioxo-2-thioxohexaydropyrimidin-5-ide 3 via a regioselective Michael addition of N,N-diethylthiobarbituric acid 1 to dienone 2 is described. In 3, the carboanion of th...

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Detalles Bibliográficos
Autores principales:	Barakat, Assem, Al-Majid, Abdullah Mohammed, Soliman, Saied M., Lotfy, Gehad, Ghabbour, Hazem A., Fun, Hoong-Kun, Wadood, Abdul, Warad, Ismail, Sloop, Joseph C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331823/ https://www.ncbi.nlm.nih.gov/pubmed/26610441 http://dx.doi.org/10.3390/molecules201119710

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