Bioactive Constituents from the Aerial Parts of Lippia triphylla

Five new compounds, lippianosides A (1), B (2), C (3), D (4), and E (5), along with 26 (6–31) known ones were obtained from the 95% EtOH extract of Lippia triphylla (L. triphylla) aerial parts collected from Rwanda, Africa. Among the known compounds, 11 and 17–30 were isolated from the Lippia genus...

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Autores principales: Zhang, Yi, Chen, Yue, Wang, Shiyu, Dong, Yongzhe, Wang, Tingting, Qu, Lu, Li, Nan, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331846/
https://www.ncbi.nlm.nih.gov/pubmed/26670227
http://dx.doi.org/10.3390/molecules201219814
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author Zhang, Yi
Chen, Yue
Wang, Shiyu
Dong, Yongzhe
Wang, Tingting
Qu, Lu
Li, Nan
Wang, Tao
author_facet Zhang, Yi
Chen, Yue
Wang, Shiyu
Dong, Yongzhe
Wang, Tingting
Qu, Lu
Li, Nan
Wang, Tao
author_sort Zhang, Yi
collection PubMed
description Five new compounds, lippianosides A (1), B (2), C (3), D (4), and E (5), along with 26 (6–31) known ones were obtained from the 95% EtOH extract of Lippia triphylla (L. triphylla) aerial parts collected from Rwanda, Africa. Among the known compounds, 11 and 17–30 were isolated from the Lippia genus for the first time. In addition, 12, 13, and 16 were firstly obtained from this species. The structures of them were elucidated by chemical and spectroscopic methods. The antioxidant and triglyceride accumulation inhibition effects of the 31 compounds were examined in L6 cells and HepG2 cells, respectively.
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spelling pubmed-63318462019-01-24 Bioactive Constituents from the Aerial Parts of Lippia triphylla Zhang, Yi Chen, Yue Wang, Shiyu Dong, Yongzhe Wang, Tingting Qu, Lu Li, Nan Wang, Tao Molecules Article Five new compounds, lippianosides A (1), B (2), C (3), D (4), and E (5), along with 26 (6–31) known ones were obtained from the 95% EtOH extract of Lippia triphylla (L. triphylla) aerial parts collected from Rwanda, Africa. Among the known compounds, 11 and 17–30 were isolated from the Lippia genus for the first time. In addition, 12, 13, and 16 were firstly obtained from this species. The structures of them were elucidated by chemical and spectroscopic methods. The antioxidant and triglyceride accumulation inhibition effects of the 31 compounds were examined in L6 cells and HepG2 cells, respectively. MDPI 2015-12-08 /pmc/articles/PMC6331846/ /pubmed/26670227 http://dx.doi.org/10.3390/molecules201219814 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Yi
Chen, Yue
Wang, Shiyu
Dong, Yongzhe
Wang, Tingting
Qu, Lu
Li, Nan
Wang, Tao
Bioactive Constituents from the Aerial Parts of Lippia triphylla
title Bioactive Constituents from the Aerial Parts of Lippia triphylla
title_full Bioactive Constituents from the Aerial Parts of Lippia triphylla
title_fullStr Bioactive Constituents from the Aerial Parts of Lippia triphylla
title_full_unstemmed Bioactive Constituents from the Aerial Parts of Lippia triphylla
title_short Bioactive Constituents from the Aerial Parts of Lippia triphylla
title_sort bioactive constituents from the aerial parts of lippia triphylla
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331846/
https://www.ncbi.nlm.nih.gov/pubmed/26670227
http://dx.doi.org/10.3390/molecules201219814
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