Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity

The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2–24) were confirmed by FT-IR, (1)H-, (13)C-, (11)B-, (19)F-, and (31)P-NMR spectroscopy and mass spectrometry...

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Detalles Bibliográficos
Autor principal: Messali, Mouslim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331848/
https://www.ncbi.nlm.nih.gov/pubmed/26287148
http://dx.doi.org/10.3390/molecules200814936
Descripción
Sumario:The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2–24) were confirmed by FT-IR, (1)H-, (13)C-, (11)B-, (19)F-, and (31)P-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl)pyridinium derivatives 5 and 19.

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