Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction

Synthetic modification of trichlorofluoromethane (CFCl(3)) to non-volatile and useful fluorinated precursors is a cost-effective and an environmentally benign strategy for the safe consumption/destruction of the ozone depleting potential of the reagent. In this report, we present a novel method for...

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Detalles Bibliográficos
Autores principales: Barkakaty, Balaka, Talukdar, Bandana, Lokitz, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331902/
https://www.ncbi.nlm.nih.gov/pubmed/26295221
http://dx.doi.org/10.3390/molecules200815098
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author Barkakaty, Balaka
Talukdar, Bandana
Lokitz, Bradley S.
author_facet Barkakaty, Balaka
Talukdar, Bandana
Lokitz, Bradley S.
author_sort Barkakaty, Balaka
collection PubMed
description Synthetic modification of trichlorofluoromethane (CFCl(3)) to non-volatile and useful fluorinated precursors is a cost-effective and an environmentally benign strategy for the safe consumption/destruction of the ozone depleting potential of the reagent. In this report, we present a novel method for in situ Grignard reaction using magnesium powder and CFCl(3) for synthesis of dichlorofluoromethyl aromatic alcohols.
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spelling pubmed-63319022019-01-24 Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction Barkakaty, Balaka Talukdar, Bandana Lokitz, Bradley S. Molecules Article Synthetic modification of trichlorofluoromethane (CFCl(3)) to non-volatile and useful fluorinated precursors is a cost-effective and an environmentally benign strategy for the safe consumption/destruction of the ozone depleting potential of the reagent. In this report, we present a novel method for in situ Grignard reaction using magnesium powder and CFCl(3) for synthesis of dichlorofluoromethyl aromatic alcohols. MDPI 2015-08-18 /pmc/articles/PMC6331902/ /pubmed/26295221 http://dx.doi.org/10.3390/molecules200815098 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barkakaty, Balaka
Talukdar, Bandana
Lokitz, Bradley S.
Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction
title Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction
title_full Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction
title_fullStr Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction
title_full_unstemmed Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction
title_short Addition of CFCl(3) to Aromatic Aldehydes via in Situ Grignard Reaction
title_sort addition of cfcl(3) to aromatic aldehydes via in situ grignard reaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331902/
https://www.ncbi.nlm.nih.gov/pubmed/26295221
http://dx.doi.org/10.3390/molecules200815098
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