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7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer’s Disease Treatment

Alzheimer’s disease (AD) is a debilitating progressive neurodegenerative disorder that ultimately leads to the patient’s death. Despite the fact that novel pharmacological approaches endeavoring to block the neurodegenerative process are still emerging, none of them have reached use in clinical prac...

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Detalles Bibliográficos
Autores principales: Korabecny, Jan, Andrs, Martin, Nepovimova, Eugenie, Dolezal, Rafael, Babkova, Katerina, Horova, Anna, Malinak, David, Mezeiova, Eva, Gorecki, Lukas, Sepsova, Vendula, Hrabinova, Martina, Soukup, Ondrej, Jun, Daniel, Kuca, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331912/
https://www.ncbi.nlm.nih.gov/pubmed/26690394
http://dx.doi.org/10.3390/molecules201219836