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Mimicking the Lipid Peroxidation Inhibitory Activity of Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) by Using Fatty Acid Conjugates of a Water-Soluble Selenolane

A series of fatty acid conjugates of trans-3,4-dihydroxy-1-selenolane (DHS) were synthesized by reacting DHS with appropriate acid chlorides. The obtained monoesters were evaluated for their antioxidant capacities by the lipid peroxidation assay using a lecithin/cholesterol liposome as a model syste...

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Detalles Bibliográficos
Autores principales: Iwaoka, Michio, Katakura, Arisa, Mishima, Jun, Ishihara, Yoshimi, Kunwar, Amit, Priyadarsini, Kavirayani Indira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331923/
https://www.ncbi.nlm.nih.gov/pubmed/26198222
http://dx.doi.org/10.3390/molecules200712364