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Serum Neurofilament light correlates with CADASIL disease severity and survival

OBJECTIVE: To validate whether serum Neurofilament Light‐chain (NfL) levels correlate with disease severity in CADASIL, and to determine whether serum NfL predicts disease progression and survival. METHODS: Fourty‐one (pre‐) manifest individuals with CADASIL causing NOTCH3 mutations and 22 healthy c...

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Detalles Bibliográficos
Autores principales:	Gravesteijn, Gido, Rutten, Julie W., Verberk, Inge M. W., Böhringer, Stefan, Liem, Michael K., van der Grond, Jeroen, Aartsma‐Rus, Annemieke, Teunissen, Charlotte E., Lesnik Oberstein, Saskia A. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331956/ https://www.ncbi.nlm.nih.gov/pubmed/30656183 http://dx.doi.org/10.1002/acn3.678

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