Design and Synthesis of New 2-Aryl-4,5-dihydro-thiazole Analogues: In Vitro Antibacterial Activities and Preliminary Mechanism of Action

Sixty 2-aryl-4,5-dihydrothiazoles were designed and synthesized in yields ranging from 64% to 89% from cysteine and substituted-benzonitriles via a novel metal- and catalyst-free method. The structures of the title compounds were confirmed mainly by NMR spectral data analysis. Antibacterial activity...

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Detalles Bibliográficos
Autores principales: Tan, Fangfang, Shi, Baojun, Li, Jian, Wu, Wenjun, Zhang, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331989/
https://www.ncbi.nlm.nih.gov/pubmed/26569197
http://dx.doi.org/10.3390/molecules201119680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331989/
https://www.ncbi.nlm.nih.gov/pubmed/26569197
http://dx.doi.org/10.3390/molecules201119680

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