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Synthesis, Crystal Structure, Absolute Configuration and Antitumor Activity of the Enantiomers of 5-Bromo-2-chloro-N-(1-phenylethyl)pyridine-3-sulfonamide

Pyridinesulfonamide is an important fragment which has a wide range of applications in novel drugs. R- and S-isomers of 5-bromo-2-chloro-N-(1-phenylethyl)pyridine-3-sulfonamide have been synthesized, and the stereostructures have been researched. Single crystals of both compounds were obtained for X...

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Detalles Bibliográficos
Autores principales: Zhou, Zhixu, Li, Linwei, Yan, Ning, Du, Lei, Sun, Changshan, Sun, Tiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332033/
https://www.ncbi.nlm.nih.gov/pubmed/26610458
http://dx.doi.org/10.3390/molecules201119740

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