New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.

Two new ent-kaurane diterpene glycosides, ranunculosides A (1) and B (2), and a new benzophenone, ranunculone C (3), were isolated from the aerial part of Ranunculus muricatus Linn. The chemical structures of compounds 1–3 were established to be (2S)-ent-kauran-2β-ol-15-en-14-O-β-d-glucopyranoside,...

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Autores principales: Wu, Bi-Ling, Zou, Hui-Liang, Qin, Fang-Min, Li, Hong-Yu, Zhou, Guang-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332058/
https://www.ncbi.nlm.nih.gov/pubmed/26694331
http://dx.doi.org/10.3390/molecules201219801
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author Wu, Bi-Ling
Zou, Hui-Liang
Qin, Fang-Min
Li, Hong-Yu
Zhou, Guang-Xiong
author_facet Wu, Bi-Ling
Zou, Hui-Liang
Qin, Fang-Min
Li, Hong-Yu
Zhou, Guang-Xiong
author_sort Wu, Bi-Ling
collection PubMed
description Two new ent-kaurane diterpene glycosides, ranunculosides A (1) and B (2), and a new benzophenone, ranunculone C (3), were isolated from the aerial part of Ranunculus muricatus Linn. The chemical structures of compounds 1–3 were established to be (2S)-ent-kauran-2β-ol-15-en-14-O-β-d-glucopyranoside, (2S,4S)-ent-kauran-2β,18-diol-15-en-14-O-β-d-glucopyranoside, and (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxy-phenyl]-2-hydroxylpropanoic acid, respectively, by spectroscopic data and chemical methods. The absolute configuration of 1 was determined by the combinational application of RP-HPLC analysis and Mosher’s method.
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spelling pubmed-63320582019-01-24 New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. Wu, Bi-Ling Zou, Hui-Liang Qin, Fang-Min Li, Hong-Yu Zhou, Guang-Xiong Molecules Article Two new ent-kaurane diterpene glycosides, ranunculosides A (1) and B (2), and a new benzophenone, ranunculone C (3), were isolated from the aerial part of Ranunculus muricatus Linn. The chemical structures of compounds 1–3 were established to be (2S)-ent-kauran-2β-ol-15-en-14-O-β-d-glucopyranoside, (2S,4S)-ent-kauran-2β,18-diol-15-en-14-O-β-d-glucopyranoside, and (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxy-phenyl]-2-hydroxylpropanoic acid, respectively, by spectroscopic data and chemical methods. The absolute configuration of 1 was determined by the combinational application of RP-HPLC analysis and Mosher’s method. MDPI 2015-12-15 /pmc/articles/PMC6332058/ /pubmed/26694331 http://dx.doi.org/10.3390/molecules201219801 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wu, Bi-Ling
Zou, Hui-Liang
Qin, Fang-Min
Li, Hong-Yu
Zhou, Guang-Xiong
New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
title New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
title_full New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
title_fullStr New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
title_full_unstemmed New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
title_short New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
title_sort new ent-kaurane-type diterpene glycosides and benzophenone from ranunculus muricatus linn.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332058/
https://www.ncbi.nlm.nih.gov/pubmed/26694331
http://dx.doi.org/10.3390/molecules201219801
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