Cargando…

G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents

Though a variety of different non-canonical nucleic acids conformations have been recognized, G-quadruplex structures are probably the structural motifs most commonly found within known oligonucleotide-based aptamers. This could be ascribed to several factors, as their large conformational diversity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Musumeci, Domenica, Riccardi, Claudia, Montesarchio, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332060/ https://www.ncbi.nlm.nih.gov/pubmed/26402662 http://dx.doi.org/10.3390/molecules200917511

Ejemplares similares

Insights into the Small Molecule Targeting of Biologically Relevant G-Quadruplexes: An Overview of NMR and Crystal Structures
por: Criscuolo, Andrea, et al.
Publicado: (2022)

G-quadruplex-based aptamers against protein targets in therapy and diagnostics()
por: Platella, Chiara, et al.
Publicado: (2017)

Disentangling the Structure–Activity Relationships of Naphthalene Diimides as Anticancer G-Quadruplex-Targeting Drugs
por: Platella, Chiara, et al.
Publicado: (2021)

Affinity Chromatography‐Based Assays for the Screening of Potential Ligands Selective for G‐Quadruplex Structures
por: Platella, Chiara, et al.
Publicado: (2022)

Insights into the G-rich VEGF-binding aptamer V7t1: when two G-quadruplexes are better than one!
por: Moccia, Federica, et al.
Publicado: (2019)

Exploring the Binding of Natural Compounds to Cancer-Related G-Quadruplex Structures: From 9,10-Dihydrophenanthrenes to Their Dimeric and Glucoside Derivatives
por: Platella, Chiara, et al.
Publicado: (2023)

Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography
por: Platella, Chiara, et al.
Publicado: (2020)

Tuning the Polymorphism of the Anti-VEGF G-rich V7t1 Aptamer by Covalent Dimeric Constructs
por: Riccardi, Claudia, et al.
Publicado: (2020)

Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition
por: Riccardi, Claudia, et al.
Publicado: (2020)

Synthesis of a Cholesteryl-HEG Phosphoramidite Derivative and Its Application to Lipid-conjugates of the Anti-HIV (5')TGGGAG(3') Hotoda’s Sequence
por: Musumeci, Domenica, et al.
Publicado: (2012)

Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics
por: Musumeci, Domenica, et al.
Publicado: (2017)

Charge-Transfer Interactions Stabilize G-Quadruplex-Forming Thrombin Binding Aptamers and Can Improve Their Anticoagulant Activity
por: Pérez de Carvasal, Kévan, et al.
Publicado: (2021)

Selective Targeting of Cancer-Related G-Quadruplex Structures by the Natural Compound Dicentrine
por: Platella, Chiara, et al.
Publicado: (2023)

Design, Synthesis, and Characterization of an Amphiphilic Lipoic Acid-Based Ru(III) Complex as a Versatile Tool for the Functionalization of Different Nanosystems
por: Riccardi, Claudia, et al.
Publicado: (2023)

DNA Binding Mode Analysis of a Core-Extended Naphthalene Diimide as a Conformation-Sensitive Fluorescent Probe of G-Quadruplex Structures
por: Platella, Chiara, et al.
Publicado: (2021)

Structure and Stability of a Dimeric G-Quadruplex Formed by Cyclic Oligonucleotides
por: Casals, Joan, et al.
Publicado: (2010)

Anticancer Ruthenium(III) Complexes and Ru(III)-Containing Nanoformulations: An Update on the Mechanism of Action and Biological Activity
por: Riccardi, Claudia, et al.
Publicado: (2019)

Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better!
por: Riccardi, Claudia, et al.
Publicado: (2022)

Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide
por: Voges, Maike, et al.
Publicado: (2016)

The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
por: Saccà, Barbara, et al.
Publicado: (2005)

G-Quadruplex Nucleic Acids
por: Eritja, Ramon, et al.
Publicado: (2010)

Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity(†)
por: Do, Ngoc Quang, et al.
Publicado: (2011)

The G-Quadruplex Ligand Telomestatin Impairs Binding of Topoisomerase IIIα to G-Quadruplex-Forming Oligonucleotides and Uncaps Telomeres in ALT Cells
por: Temime-Smaali, Nassima, et al.
Publicado: (2009)

Spectroscopic Properties of Two 5′-(4-Dimethylamino)Azobenzene Conjugated G-Quadruplex Forming Oligonucleotides
por: Imperatore, Concetta, et al.
Publicado: (2020)

Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies
por: Riccardi, Claudia, et al.
Publicado: (2022)

Putative HIV and SIV G-Quadruplex Sequences in Coding and Noncoding Regions Can Form G-Quadruplexes
por: Krafčíková, Petra, et al.
Publicado: (2017)

Hole Migration in Telomere‐Based Oligonucleotide Anions and G‐Quadruplexes
por: Li, Wen, et al.
Publicado: (2019)

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes
por: Riccardi, Claudia, et al.
Publicado: (2020)

G-Quadruplex-Forming Aptamers—Characteristics, Applications, and Perspectives
por: Roxo, Carolina, et al.
Publicado: (2019)

Beyond small molecules: targeting G-quadruplex structures with oligonucleotides and their analogues
por: Cadoni, Enrico, et al.
Publicado: (2021)

Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex
por: Ryazantsev, Dmitriy Y., et al.
Publicado: (2021)

Detection of CpG Methylation in G-Quadruplex Forming Sequences Using G-Quadruplex Ligands
por: Hasegawa, Hijiri, et al.
Publicado: (2021)

On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight
por: Platella, Chiara, et al.
Publicado: (2020)

Design and Properties of Ligand-Conjugated Guanine Oligonucleotides for Recovery of Mutated G-Quadruplexes
por: Takahashi, Shuntaro, et al.
Publicado: (2018)

Short LNA-modified oligonucleotide probes as efficient disruptors of DNA G-quadruplexes
por: Chowdhury, Souroprobho, et al.
Publicado: (2022)

G4 Matters—The Influence of G-Quadruplex Structural Elements on the Antiproliferative Properties of G-Rich Oligonucleotides
por: Roxo, Carolina, et al.
Publicado: (2021)

Identification of RNA Oligonucleotides Binding to Several Proteins from Potential G-Quadruplex Forming Regions in Transcribed Pre-mRNA
por: Saito, Taiki, et al.
Publicado: (2015)

Modulation of Aptamer–Ligand-Binding by Complementary Oligonucleotides: A G-Quadruplex Anti-Ochratoxin A Aptamer Case Study
por: Samokhvalov, Alexey V., et al.
Publicado: (2022)

Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes
por: Solé, Anna, et al.
Publicado: (2017)

Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches
por: Rouleau, Samuel G., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kfnu2kkfcqahh7oq2spbr590j5