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Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids

Major problems of cancer treatment using systemic chemotherapy are severe side effects. Magnetic drug targeting (MDT) employing superparamagnetic iron oxide nanoparticles (SPION) loaded with chemotherapeutic agents may overcome this dilemma by increasing drug accumulation in the tumor and reducing t...

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Detalles Bibliográficos
Autores principales:	Hornung, Annkathrin, Poettler, Marina, Friedrich, Ralf P., Zaloga, Jan, Unterweger, Harald, Lyer, Stefan, Nowak, Johannes, Odenbach, Stefan, Alexiou, Christoph, Janko, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332068/ https://www.ncbi.nlm.nih.gov/pubmed/26437393 http://dx.doi.org/10.3390/molecules201018016

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