New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)

Clusia nemorosa has been widely used in folk medicine to treat various ailments, including headaches and inflammation. Investigation of the fruits of Clusia nemorosa (Clusiaceae) led to the isolation and characterization of a new phloroglucinol derivative, named 6S,8S,28S-nemorosic acid (1), togethe...

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Autores principales: Oliveira Ferreira, Rafaela, Maria Sarmento da Silva, Tania, Geraldo de Carvalho, Mário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332069/
https://www.ncbi.nlm.nih.gov/pubmed/26287129
http://dx.doi.org/10.3390/molecules200814326
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author Oliveira Ferreira, Rafaela
Maria Sarmento da Silva, Tania
Geraldo de Carvalho, Mário
author_facet Oliveira Ferreira, Rafaela
Maria Sarmento da Silva, Tania
Geraldo de Carvalho, Mário
author_sort Oliveira Ferreira, Rafaela
collection PubMed
description Clusia nemorosa has been widely used in folk medicine to treat various ailments, including headaches and inflammation. Investigation of the fruits of Clusia nemorosa (Clusiaceae) led to the isolation and characterization of a new phloroglucinol derivative, named 6S,8S,28S-nemorosic acid (1), together with seven known compounds: friedelin (2), β-sitosterol (3), stigmasterol (4), β-sitosterol glycoside (5), kaempferol (6), quercetin (7) and dimethyl citrate (8). The structures were determined by extensive 1D- and 2D-NMR, CD and MS spectroscopic analyses.
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spelling pubmed-63320692019-01-24 New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae) Oliveira Ferreira, Rafaela Maria Sarmento da Silva, Tania Geraldo de Carvalho, Mário Molecules Article Clusia nemorosa has been widely used in folk medicine to treat various ailments, including headaches and inflammation. Investigation of the fruits of Clusia nemorosa (Clusiaceae) led to the isolation and characterization of a new phloroglucinol derivative, named 6S,8S,28S-nemorosic acid (1), together with seven known compounds: friedelin (2), β-sitosterol (3), stigmasterol (4), β-sitosterol glycoside (5), kaempferol (6), quercetin (7) and dimethyl citrate (8). The structures were determined by extensive 1D- and 2D-NMR, CD and MS spectroscopic analyses. MDPI 2015-08-06 /pmc/articles/PMC6332069/ /pubmed/26287129 http://dx.doi.org/10.3390/molecules200814326 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oliveira Ferreira, Rafaela
Maria Sarmento da Silva, Tania
Geraldo de Carvalho, Mário
New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)
title New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)
title_full New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)
title_fullStr New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)
title_full_unstemmed New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)
title_short New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)
title_sort new polyprenylated phloroglucinol and other compounds isolated from the fruits of clusia nemorosa (clusiaceae)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332069/
https://www.ncbi.nlm.nih.gov/pubmed/26287129
http://dx.doi.org/10.3390/molecules200814326
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