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A Practical Route for the Preparation of 1,4,7-Triazacyclononanyl Diacetates with a Hydroxypyridinonate Pendant Arm

The preparation of triazamacrocyclic hydroxypyridinonate (HOPO-TACN) derivatives as potential chelators for metals in biomedical applications was reported. The synthesis is based on a convergent synthetic approach, in which the key intermediate di-tert-butyl-2,2′-(1,4,7-triazonane-1,4-diyl) diacetat...

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Detalles Bibliográficos
Autores principales: Gai, Yongkang, Hu, Zhongping, Rong, Zhao, Ma, Xiang, Xiang, Guangya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332087/
https://www.ncbi.nlm.nih.gov/pubmed/26512638
http://dx.doi.org/10.3390/molecules201019393