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A Combined Molecular Docking/Dynamics Approach to Probe the Binding Mode of Cancer Drugs with Cytochrome P450 3A4

Cytarabine, daunorubicin, doxorubicin and vincristine are clinically used for combinatorial therapies of cancers in different combinations. However, the knowledge about the interaction of these drugs with the metabolizing enzyme cytochrome P450 is limited. Therefore, we utilized computational method...

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Detalles Bibliográficos
Autores principales:	Panneerselvam, Suresh, Yesudhas, Dhanusha, Durai, Prasannavenkatesh, Anwar, Muhammad Ayaz, Gosu, Vijayakumar, Choi, Sangdun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332164/ https://www.ncbi.nlm.nih.gov/pubmed/26287147 http://dx.doi.org/10.3390/molecules200814915

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