Cargando…

Study of the Relationships between the Structure, Lipophilicity and Biological Activity of Some Thiazolyl-carbonyl-thiosemicarbazides and Thiazolyl-azoles

Lipophilicity, as one of the most important physicochemical parameters of bioactive molecules, was investigated for twenty-two thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azoles. The determination was carried out by reversed-phase thin-layer chromatography, using a binary isopropanol-water m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tamaian, Radu, Moţ, Augustin, Silaghi-Dumitrescu, Radu, Ionuţ, Ioana, Stana, Anca, Oniga, Ovidiu, Nastasă, Cristina, Benedec, Daniela, Tiperciuc, Brînduşa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332165/ https://www.ncbi.nlm.nih.gov/pubmed/26690402 http://dx.doi.org/10.3390/molecules201219841

Ejemplares similares

Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors
por: Nastasă, Cristina, et al.
Publicado: (2018)

New Thiazolyl-triazole Schiff Bases: Synthesis and Evaluation of the Anti-Candida Potential
por: Stana, Anca, et al.
Publicado: (2016)

Synthesis, lipophilicity and antimicrobial activity evaluation of some new thiazolyl-oxadiazolines
por: STOICA, CRISTINA IOANA, et al.
Publicado: (2015)

5-Arylidene(chromenyl-methylene)-thiazolidinediones: Potential New Agents against Mutant Oncoproteins K-Ras, N-Ras and B-Raf in Colorectal Cancer and Melanoma
por: Nastasă, Cristina, et al.
Publicado: (2019)

Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitors
por: Stana, Anca, et al.
Publicado: (2019)

Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors
por: Stana, Anca, et al.
Publicado: (2017)

A Novel Thiazolyl Schiff Base: Antibacterial and Antifungal Effects and In Vitro Oxidative Stress Modulation on Human Endothelial Cells
por: Login, Cristian Cezar, et al.
Publicado: (2019)

New Hydrazones Bearing Thiazole Scaffold: Synthesis, Characterization, Antimicrobial, and Antioxidant Investigation
por: Nastasă, Cristina, et al.
Publicado: (2015)

Achillea schurii Flowers: Chemical, Antioxidant, and Antimicrobial Investigations
por: Benedec, Daniela, et al.
Publicado: (2016)

Synthesis of New Phenolic Derivatives of Quinazolin-4(3H)-One as Potential Antioxidant Agents—In Vitro Evaluation and Quantum Studies
por: Pele, Raluca, et al.
Publicado: (2022)

Sources for developing new medicinal products: biochemical investigations on alcoholic extracts obtained from aerial parts of some Romanian Amaryllidaceae species
por: Benedec, Daniela, et al.
Publicado: (2018)

Polyphenolic Composition, Antioxidant and Antibacterial Activities for Two Romanian Subspecies of Achillea distans Waldst. et Kit. ex Willd
por: Benedec, Daniela, et al.
Publicado: (2013)

Synthesis and Antiproliferative Activity of Thiazolyl-bis-pyrrolo[2,3-b]pyridines and Indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, Nortopsentin Analogues
por: Carbone, Anna, et al.
Publicado: (2015)

Stachys Species: Comparative Evaluation of Phenolic Profile and Antimicrobial and Antioxidant Potential
por: Benedec, Daniela, et al.
Publicado: (2023)

Microwave-assisted synthesis and antioxidant properties of hydrazinyl thiazolyl coumarin derivatives
por: Osman, Hasnah, et al.
Publicado: (2012)

An Efficient Synthesis of Novel Bioactive Thiazolyl-Phthalazinediones under Ultrasound Irradiation
por: Elsharabasy, Fatma S., et al.
Publicado: (2017)

Structure-Activity Relationships of Thiazolyl Resorcinols, Potent and Selective Inhibitors of Human Tyrosinase
por: Mann, Tobias, et al.
Publicado: (2018)

Development of novel isatin thiazolyl-pyrazoline hybrids as promising antimicrobials in MDR pathogens
por: Al-Warhi, Tarfah, et al.
Publicado: (2022)

Development of new 5-(chromene-3-yl)methylene-2,4-thiazolidinediones as antimicrobial agents
por: NASTASĂ, CRISTINA MARIANA, et al.
Publicado: (2016)

Sponge-Derived Kocuria and Micrococcus spp. as Sources of the New Thiazolyl Peptide Antibiotic Kocurin
por: Palomo, Sara, et al.
Publicado: (2013)

Computational and biological studies of novel thiazolyl coumarin derivatives synthesized through Suzuki coupling
por: PARVEEN, Shaista, et al.
Publicado: (2020)

Effective reduction of post‐inflammatory hyperpigmentation with the tyrosinase inhibitor isobutylamido‐thiazolyl‐resorcinol (Thiamidol)
por: Roggenkamp, Dennis, et al.
Publicado: (2021)

Lipophilicity Studies on Thiosemicarbazide Derivatives
por: Paneth, Agata, et al.
Publicado: (2017)

Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
por: Altıntop, Mehlika Dilek, et al.
Publicado: (2014)

Synthesis of Oxadiazolyl, Pyrazolyl and Thiazolyl Derivatives of Thiophene-2-Carboxamide as Antimicrobial and Anti-HCV Agents
por: Rizk, Ola H., et al.
Publicado: (2017)

Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents
por: Sayed, Abdelwahed R., et al.
Publicado: (2019)

Synthesis and Molecular Docking of Some Novel 3-Thiazolyl-Coumarins as Inhibitors of VEGFR-2 Kinase
por: Abolibda, Tariq Z., et al.
Publicado: (2023)

Protein-Based Blood Substitutes: Recent Attempts at Controlling Pro-Oxidant Reactivity With and Beyond Hemoglobin
por: Scurtu, Violeta-Florina, et al.
Publicado: (2013)

Experimental and Theoretical Investigation of Thiazolyl Blue as a Corrosion Inhibitor for Copper in Neutral Sodium Chloride Solution
por: Feng, Li, et al.
Publicado: (2018)

Application of Docking Analysis in the Prediction and Biological Evaluation of the Lipoxygenase Inhibitory Action of Thiazolyl Derivatives of Mycophenolic Acid
por: Tsolaki, Evangelia, et al.
Publicado: (2018)

Synthesis and Biological Evaluation of Novel Thiazolyl-Coumarin Derivatives as Potent Histone Deacetylase Inhibitors with Antifibrotic Activity
por: Pardo-Jiménez, Viviana, et al.
Publicado: (2019)

Synthesis, Characterization and Molecular Docking of Novel Bioactive Thiazolyl-Thiazole Derivatives as Promising Cytotoxic Antitumor Drug
por: Gomha, Sobhi M., et al.
Publicado: (2015)

Identification and characterization of a phenyl-thiazolyl-benzoic acid derivative as a novel RAR/RXR agonist
por: Koshiishi, Chie, et al.
Publicado: (2019)

Investigating novel thiazolyl-indazole derivatives as scaffolds for SARS-CoV-2 M(Pro) inhibitors
por: Airas, Justin, et al.
Publicado: (2022)

Evaluation of Antioxidant and Antimicrobial Activities and Phenolic Profile for Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys
por: Vlase, Laurian, et al.
Publicado: (2014)

Efficient adsorptive removal of paracetamol and thiazolyl blue from polluted water onto biosynthesized copper oxide nanoparticles
por: Akpomie, Kovo G., et al.
Publicado: (2023)

Synthesis of Schiff Bases and Isoindolyl- and Thiazolyl-Substituted Quinolines from 6-Amino-2-methylquinolin-4-ol
por: Aleqsanyan, I. L., et al.
Publicado: (2022)

Synthesis, In Vitro Evaluation and Molecular Docking Studies of Novel Thiophenyl Thiazolyl-Pyridine Hybrids as Potential Anticancer Agents
por: Ashmawy, Fayza O., et al.
Publicado: (2023)

Thermally Activated Delayed Fluorescence in Neutral and Cationic Copper(I) Complexes with the 2-(4-Thiazolyl)benzimidazole Ligand
por: Alconchel, Adrián, et al.
Publicado: (2023)

Different patterns of supramolecular aggregation in three amides containing N-(benzo[d]thiazolyl) substituents
por: Mahesha, Ninganayaka, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rmtcjdgl22800q1m4cdd7tvf2t