Novel 3-Amino-6-chloro-7-(azol-2 or 5-yl)-1,1-dioxo-1,4,2-benzodithiazine Derivatives with Anticancer Activity: Synthesis and QSAR Study

A series of new 3-amino-6-chloro-7-(azol-2 or 5-yl)-1,1-dioxo-1,4,2-benzodithiazine derivatives 5a–j have been synthesized and evaluated in vitro for their antiproliferative activity at the U.S. National Cancer Institute. The most active compound 5h showed significant cytotoxic effects against ovari...

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Detalles Bibliográficos
Autores principales: Pogorzelska, Aneta, Sławiński, Jarosław, Brożewicz, Kamil, Ulenberg, Szymon, Bączek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332169/
https://www.ncbi.nlm.nih.gov/pubmed/26690109
http://dx.doi.org/10.3390/molecules201219821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332169/
https://www.ncbi.nlm.nih.gov/pubmed/26690109
http://dx.doi.org/10.3390/molecules201219821

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