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Relationship between Structure and Conformational Change of the Vitamin D Receptor Ligand Binding Domain in 1α,25-Dihydroxyvitamin D3 Signaling

Vitamin D Receptor (VDR) belongs to the nuclear receptor (NR) superfamily. Whereas the structure of the ligand binding domain (LBD) of VDR has been determined in great detail, the role of its amino acid residues in stabilizing the structure and ligand triggering conformational change is still under...

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Detalles Bibliográficos
Autores principales: Wan, Lin-Yan, Zhang, Yan-Qiong, Chen, Meng-Di, Du, You-Qin, Liu, Chang-Bai, Wu, Jiang-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332228/
https://www.ncbi.nlm.nih.gov/pubmed/26593892
http://dx.doi.org/10.3390/molecules201119713

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