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Relationship between Structure and Conformational Change of the Vitamin D Receptor Ligand Binding Domain in 1α,25-Dihydroxyvitamin D3 Signaling
Vitamin D Receptor (VDR) belongs to the nuclear receptor (NR) superfamily. Whereas the structure of the ligand binding domain (LBD) of VDR has been determined in great detail, the role of its amino acid residues in stabilizing the structure and ligand triggering conformational change is still under...
Autores principales: | Wan, Lin-Yan, Zhang, Yan-Qiong, Chen, Meng-Di, Du, You-Qin, Liu, Chang-Bai, Wu, Jiang-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332228/ https://www.ncbi.nlm.nih.gov/pubmed/26593892 http://dx.doi.org/10.3390/molecules201119713 |
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