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Flow Synthesis of 2-Methylpyridines via α-Methylation

A series of simple 2-methylpyridines were synthesized in an expedited and convenient manner using a simplified bench-top continuous flow setup. The reactions proceeded with a high degree of selectivity, producing α-methylated pyridines in a much greener fashion than is possible using conventional ba...

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Detalles Bibliográficos
Autores principales: Manansala, Camille, Tranmer, Geoffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332231/
https://www.ncbi.nlm.nih.gov/pubmed/26334262
http://dx.doi.org/10.3390/molecules200915797