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Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

A new route to 3-(4-arylmethylamino)butyl-5-arylidene-2-thioxo-1,3-thiazolidine-4-one 9 was developed in six steps from commercial 1,4-diaminobutane 1 as starting material. The key step of this multi-step synthesis involved a solution phase “one-pot two-steps” approach assisted by microwave dielectr...

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Detalles Bibliográficos
Autores principales: Dago, Camille Déliko, Ambeu, Christelle N´ta, Coulibaly, Wacothon-Karime, Békro, Yves-Alain, Mamyrbékova, Janat, Defontaine, Audrey, Baratte, Blandine, Bach, Stéphane, Ruchaud, Sandrine, Le Guével, Rémy, Ravache, Myriam, Corlu, Anne, Bazureau, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332318/
https://www.ncbi.nlm.nih.gov/pubmed/26184130
http://dx.doi.org/10.3390/molecules200712412