Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications

Hypoxia-inducible factor (HIF) prolyl hydroxylases (PHDs) are members of the 2-oxoglutarate dependent non-heme iron dioxygenases. Due to their physiological roles in regulation of HIF-1α stability, many efforts have been focused on searching for selective PHD inhibitors to control HIF-1α levels for...

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Detalles Bibliográficos
Autores principales: Kim, So Yeon, Yang, Eun Gyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332328/
https://www.ncbi.nlm.nih.gov/pubmed/26610437
http://dx.doi.org/10.3390/molecules201119717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332328/
https://www.ncbi.nlm.nih.gov/pubmed/26610437
http://dx.doi.org/10.3390/molecules201119717

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