Cargando…

Pharmacokinetics of Ginkgolide B after Oral Administration of Three Different Ginkgolide B Formulations in Beagle Dogs

Ginkgolide B (GB), an important active constituent of Ginkgo biloba extract, has been used in clinical applications for the treatment of dementia, cerebral insufficiency or related cognitive decline. To investigate the main pharmacokinetic characteristics of three different GB formulations in beagle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Jie, Geng, Ting, Wang, Qi, Si, Haihong, Sun, Xiaoping, Guo, Qingming, Li, Yanjing, Huang, Wenzhe, Ding, Gang, Xiao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332382/ https://www.ncbi.nlm.nih.gov/pubmed/26561795 http://dx.doi.org/10.3390/molecules201119678

Ejemplares similares

Correction: Zhao, J., et al. Pharmacokinetics of Ginkgolide B after Oral Administration of Three Different Ginkgolide B Formulations in Beagle Dogs. Molecules 2015, 20, 20031–20041
por: Zhao, Jie, et al.
Publicado: (2016)

Transformation of multi-component ginkgolide into ginkgolide B by Coprinus comatus
por: Ding, HongXue, et al.
Publicado: (2015)

Optimizing the Formulation for Ginkgolide B Solid Dispersion
por: Wu, Xiao, et al.
Publicado: (2018)

Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen-glucose deprivation
por: Yu, Wen-Bo, et al.
Publicado: (2018)

Biosynthesis pathways of ginkgolides
por: Zeng, Zihan, et al.
Publicado: (2013)

Neuroregulatory role of ginkgolides
por: Gachowska, Martyna, et al.
Publicado: (2021)

Ginkgolide B Modulates BDNF Expression in Acute Ischemic Stroke
por: Wei, Hu, et al.
Publicado: (2017)

Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β(1-42)
por: Bate, Clive, et al.
Publicado: (2004)

Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE(−/−) Mice
por: Liu, Xiyun, et al.
Publicado: (2012)

Ginkgolide B preconditioning protects neurons against ischaemia-induced apoptosis
por: Wu, Xiaomei, et al.
Publicado: (2009)

Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson’s Disease
por: Wu, Tingting, et al.
Publicado: (2020)

Dynamic Balance of Microglia and Astrocytes Involved in the Remyelinating Effect of Ginkgolide B
por: Yin, Jun-Jun, et al.
Publicado: (2020)

Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathways
por: Li, Yousong, et al.
Publicado: (2021)

Amide Derivatives of Ginkgolide B and Their Inhibitory Effects on PAF-Induced Platelet Aggregation
por: Shang, Qiang, et al.
Publicado: (2021)

Oral administration of Ginkgolide B alleviates hypoxia-induced neuronal damage in rat hippocampus by inhibiting oxidative stress and apoptosis
por: Li, Wang, et al.
Publicado: (2019)

Local Administration of Ginkgolide B Using a Hyaluronan-Based Hydrogel Improves Wound Healing in Diabetic Mice
por: Wang, Limei, et al.
Publicado: (2022)

The Signaling Cascades of Ginkgolide B-Induced Apoptosis in MCF-7 Breast Cancer Cells
por: Chan, Wen-Hsiung
Publicado: (2007)

Ginkgolide B increases hydrogen sulfide and protects against endothelial dysfunction in diabetic rats
por: Wang, Guo-Guang, et al.
Publicado: (2015)

Ginkgolide B Protects Against Ischemic Stroke via Targeting AMPK/PINK1
por: Cao, Yile, et al.
Publicado: (2022)

Ginkgolide B ameliorates myocardial ischemia reperfusion injury in rats via inhibiting endoplasmic reticulum stress
por: Guo, Changlei, et al.
Publicado: (2019)

Ginkgolide B Regulates CDDP Chemoresistance in Oral Cancer via the Platelet-Activating Factor Receptor Pathway
por: Kawasaki, Kohei, et al.
Publicado: (2021)

Metabolite-related antidepressant action of diterpene ginkgolides in the prefrontal cortex
por: Hu, Qingchuan, et al.
Publicado: (2018)

Effect of ginkgolide K on calcium channel activity in Alzheimer's disease
por: Liu, Hongbin, et al.
Publicado: (2022)

Neuroprotective Effect of Ginkgolide B on Bupivacaine-Induced Apoptosis in SH-SY5Y Cells
por: Li, Le, et al.
Publicado: (2013)

Ginkgolide B inhibits lung cancer cells promotion via beclin-1-dependent autophagy
por: Wang, Xuan, et al.
Publicado: (2020)

Cardiac dysfunction is attenuated by ginkgolide B via reducing oxidative stress and fibrosis in diabetic rats
por: Jiang, Yu-Xin, et al.
Publicado: (2020)

Ginkgolide B for Myocardial Ischemia/Reperfusion Injury: A Preclinical Systematic Review and Meta-Analysis
por: Zhu, Peng-Chong, et al.
Publicado: (2019)

Polymeric Nanoparticles-Based Brain Delivery with Improved Therapeutic Efficacy of Ginkgolide B in Parkinson’s Disease
por: Zhao, Yuying, et al.
Publicado: (2020)

Ginkgolide B improved postoperative cognitive dysfunction by inhibiting microgliosis-mediated neuroinflammation in the hippocampus of mice
por: Luo, Ting, et al.
Publicado: (2022)

Effects of Organic Elicitors on the Recycled Production of Ginkgolide B in Immobilized Cell Cultures of Ginkgo biloba
por: Lin, Chuang-Yu, et al.
Publicado: (2023)

Pharmacokinetics of BMEDA after Intravenous Administration in Beagle Dogs
por: Chang, Chih-Hsien, et al.
Publicado: (2014)

Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo
por: Li, Yan, et al.
Publicado: (2017)

Radical Scavenging Potential of Ginkgolides and Bilobalide: Insight from Molecular Modeling
por: Zeppilli, Davide, et al.
Publicado: (2023)

Ginkgolide B inhibits platelet and monocyte adhesion in TNFα-treated HUVECs under laminar shear stress
por: Zhang, Ming, et al.
Publicado: (2018)

A Novel Anti-Inflammatory Role for Ginkgolide B in Asthma via Inhibition of the ERK/MAPK Signaling Pathway
por: Chu, Xiao, et al.
Publicado: (2011)

Ginkgolide B Ameliorates Myocardial Ischemia Reperfusion Injury in Rats via Inhibiting Endoplasmic Reticulum Stress [Retraction]
Publicado: (2020)

Ginkgolide B alleviates the inflammatory response and attenuates the activation of LPS-induced BV2 cells in vitro and in vivo
por: Sun, Miaoxuan, et al.
Publicado: (2021)

Ginkgolide B attenuates collagen-induced rheumatoid arthritis and regulates fibroblast-like synoviocytes-mediated apoptosis and inflammation
por: Xie, Chuanmei, et al.
Publicado: (2020)

Ginkgolide B Maintains Calcium Homeostasis in Hypoxic Hippocampal Neurons by Inhibiting Calcium Influx and Intracellular Calcium Release
por: Wang, Li, et al.
Publicado: (2021)

Ginkgolide B-mediated therapeutic effects on perioperative neurocognitive dysfunction are associated with the inhibition of iNOS-mediated production of NO
por: Luo, Ting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rgg1tg5ct6j786j58fnt88jarh