Cargando…

Mechanism of Breast Cancer Preventive Action of Pomegranate: Disruption of Estrogen Receptor and Wnt/β-Catenin Signaling Pathways

A pomegranate emulsion (PE), containing various bioactive phytochemicals, has recently been found to exert substantial chemopreventive effect against 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumorigenesis in rats via antiproliferative and proapoptotic actions. Nevertheless, the underlyi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mandal, Animesh, Bishayee, Anupam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332439/ https://www.ncbi.nlm.nih.gov/pubmed/26703530 http://dx.doi.org/10.3390/molecules201219853

Ejemplares similares

Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway
por: Bhatia, Deepak, et al.
Publicado: (2013)

Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways
por: Mandal, Animesh, et al.
Publicado: (2017)

Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis
por: Bishayee, Anupam, et al.
Publicado: (2016)

Trianthema portulacastrum Linn. Displays Anti-Inflammatory Responses during Chemically Induced Rat Mammary Tumorigenesis through Simultaneous and Differential Regulation of NF-κB and Nrf2 Signaling Pathways
por: Mandal, Animesh, et al.
Publicado: (2015)

Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis
por: Bhat, Mamatha, et al.
Publicado: (2021)

Estrogen Receptor 1 (ESR1) and the Wnt/β-Catenin Pathway Mediate the Effect of the Coumarin Derivative Umbelliferon on Bone Mineralization
por: Pelusi, Letizia, et al.
Publicado: (2022)

Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway
por: Zhou, Zicong, et al.
Publicado: (2022)

Estrogen attenuates TGF-β1-induced EMT in intrauterine adhesion by activating Wnt/β-catenin signaling pathway
por: Cao, Jia, et al.
Publicado: (2020)

Wnt/β-catenin pathway in arrhythmogenic cardiomyopathy
por: Lorenzon, Alessandra, et al.
Publicado: (2017)

Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways
por: Kerdivel, Gwenneg, et al.
Publicado: (2013)

Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway
por: Jeong, Woo-Jeong, et al.
Publicado: (2018)

Canonical Wnt Signaling (Wnt/β-Catenin Pathway): A Potential Target for Cancer Prevention and Therapy
por: Najafi, S Mahmoud A
Publicado: (2020)

Crosstalk between Wnt/β-Catenin and Estrogen Receptor Signaling Synergistically Promotes Osteogenic Differentiation of Mesenchymal Progenitor Cells
por: Gao, Yanhong, et al.
Publicado: (2013)

A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling
por: Geng, Ajun, et al.
Publicado: (2020)

Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
por: Wickström, Malin, et al.
Publicado: (2015)

Role of the Wnt/β-Catenin Pathway in Renal Osteodystrophy
por: Bisson, Sarah-Kim, et al.
Publicado: (2018)

Cannabidiol and the Canonical WNT/β-Catenin Pathway in Glaucoma
por: Vallée, Alexandre, et al.
Publicado: (2021)

Targeting the Wnt/β-catenin signaling pathway in cancer
por: Zhang, Ya, et al.
Publicado: (2020)

The Wnt/β-catenin signalling pathway in Haematological Neoplasms
por: Yu, Siwei, et al.
Publicado: (2022)

TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
por: Guerrero, Fátima, et al.
Publicado: (2014)

Vitamin D receptor prevents tumour development by regulating the Wnt/β-catenin signalling pathway in human colorectal cancer
por: Yu, Jie, et al.
Publicado: (2023)

A Pleiotropic Role of Long Non-Coding RNAs in the Modulation of Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathways in Esophageal Squamous Cell Carcinoma: Implication in Chemotherapeutic Drug Response
por: Sharma, Uttam, et al.
Publicado: (2022)

Roxadustat promotes osteoblast differentiation and prevents estrogen deficiency-induced bone loss by stabilizing HIF-1α and activating the Wnt/β-catenin signaling pathway
por: Li, Luyao, et al.
Publicado: (2022)

Molecular Pathways of Estrogen Receptor Action
por: Pakdel, Farzad
Publicado: (2018)

Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells
por: Morris, Saint-Aaron L., et al.
Publicado: (2016)

Parkinson’s Disease: Potential Actions of Lithium by Targeting the WNT/β-Catenin Pathway, Oxidative Stress, Inflammation and Glutamatergic Pathway
por: Vallée, Alexandre, et al.
Publicado: (2021)

Activation of Intracellular Calcium by Multiple Wnt Ligands and Translocation of β-Catenin into the Nucleus: A CONVERGENT MODEL OF Wnt/Ca(2+) AND Wnt/β-CATENIN PATHWAYS
por: Thrasivoulou, Christopher, et al.
Publicado: (2013)

Preventive and Prophylactic Mechanisms of Action of Pomegranate Bioactive Constituents
por: Viladomiu, Monica, et al.
Publicado: (2013)

MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin
por: SU, JUAN, et al.
Publicado: (2011)

KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer
por: Yao, Hanhui, et al.
Publicado: (2022)

Targeting the Wnt/β-catenin pathway in endometriosis: a potentially effective approach for treatment and prevention
por: Matsuzaki, Sachiko, et al.
Publicado: (2014)

Haemophilus parasuis Infection Disrupts Adherens Junctions and Initializes EMT Dependent on Canonical Wnt/β-Catenin Signaling Pathway
por: Hua, Kexin, et al.
Publicado: (2018)

The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres
por: Kanwar, Shailender S, et al.
Publicado: (2010)

Wnt/β-Catenin Signaling Pathway in Skin Carcinogenesis and Therapy
por: Li, Jing, et al.
Publicado: (2015)

Targeting the canonical Wnt/β-catenin pathway in hematological malignancies
por: Ashihara, Eishi, et al.
Publicado: (2015)

Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway
por: Burke, Zoë D., et al.
Publicado: (2018)

Targeting the Wnt/β-catenin pathway in human osteosarcoma cells
por: Fang, Fang, et al.
Publicado: (2018)

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer
por: Bian, Jia, et al.
Publicado: (2020)

Epigenetic Regulation of the Wnt/β-Catenin Signaling Pathway in Cancer
por: Sharma, Ankita, et al.
Publicado: (2021)

Neuroinflammation in Schizophrenia: The Key Role of the WNT/β-Catenin Pathway
por: Vallée, Alexandre
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b8f5av48l0kpb25qnkrgpvdm9e