Complete Disaggregation of MCF-7-derived Breast Tumour Spheroids with Very Low Concentrations of α-Mangostin Loaded in CD44 Thioaptamer-tagged Nanoparticles

Background: α-Mangostin (αMG) is a natural substance that exerts a wide range of antitumor effects. Recently, we described that free αMG was able to dissociate multicellular tumour spheroids (MCTSs) generated from breast carcinoma cells and to reduce their cellular viability and motility. Here, αMG...

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Detalles Bibliográficos
Autores principales: Bonafè, Francesca, Pazzini, Claudia, Marchionni, Silvia, Guarnieri, Carlo, Muscari, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332479/
https://www.ncbi.nlm.nih.gov/pubmed/30662326
http://dx.doi.org/10.7150/ijms.28135

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