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Nitrogen Containing Bisphosphonates Impair the Release of Bone Homeostasis Mediators and Matrix Production by Human Primary Pre-Osteoblasts

Bisphosphonates (BPs) represent the first-line treatment for a wide array of bone disorders. Despite their well-known action on osteoclasts, the effects they induce on osteoblasts are still unclear. In order to shed light on this aspect we evaluated the impact of two nitrogen containing bisphosphona...

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Detalles Bibliográficos
Autores principales: Giannasi, Chiara, Niada, Stefania, Farronato, Davide, Lombardi, Giovanni, Manfredi, Barbara, Farronato, Giampietro, Brini, Anna Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332484/
https://www.ncbi.nlm.nih.gov/pubmed/30662325
http://dx.doi.org/10.7150/ijms.27470