An agent-based model of the Notch signaling pathway elucidates three levels of complexity in the determination of developmental patterning

BACKGROUND: The Notch signaling pathway is involved in cell fate decision and developmental patterning in diverse organisms. A receptor molecule, Notch (N), and a ligand molecule (in this case Delta or Dl) are the central molecules in this pathway. In early Drosophila embryos, these molecules determ...

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Detalles Bibliográficos
Autores principales: Reynolds, Elaine R., Himmelwright, Ryan, Sanginiti, Christopher, Pfaffmann, Jeffrey O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332573/
https://www.ncbi.nlm.nih.gov/pubmed/30642357
http://dx.doi.org/10.1186/s12918-018-0672-9

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