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Crystal structure of E. coli PRPP synthetase

BACKGROUND: Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) is an enzyme that catalyzes the ATP-dependent conversion of ribose-5-phosphate to phosphoribosyl pyrophosphate. The reaction product is a key precursor for the biosynthesis of purine and pyrimidine nucleotides. RESULTS: We report the 2.2 Å...

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Detalles Bibliográficos
Autores principales:	Zhou, Weijie, Tsai, Andrew, Dattmore, Devon A., Stives, Devin P., Chitrakar, Iva, D’alessandro, Alexis M., Patil, Shiv, Hicks, Katherine A., French, Jarrod B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332680/ https://www.ncbi.nlm.nih.gov/pubmed/30646888 http://dx.doi.org/10.1186/s12900-019-0100-4

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