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Global mapping of binding sites for phic31 integrase in transgenic maden-darby bovine kidney cells using ChIP-seq

BACKGROUND: ΦC31 integrase, a site-specific recombinase, can efficiently target attB-bearing transgenes to endogenous pseudo attP sites within mammalian genomes. The sequence features of endogenous binding sites will help us to fully understand the site-specific recognition function by ΦC31 integras...

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Detalles Bibliográficos
Autores principales:	Qu, Lijuan, Wang, Lei, Zhu, Xueyuan, Zhang, Yan, Ou, Qiang, Ma, Aying, Sheng, Fengying, Wei, Xiaoqing, Dai, Yue, Li, Guoting, Xie, Shuwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332687/ https://www.ncbi.nlm.nih.gov/pubmed/30675136 http://dx.doi.org/10.1186/s41065-018-0079-z

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