AMYCO: evaluation of mutational impact on prion-like proteins aggregation propensity

BACKGROUND: Around 1% of human proteins are predicted to contain a disordered and low complexity prion-like domain (PrLD). Mutations in PrLDs have been shown promote a transition towards an aggregation-prone state in several diseases. RESULTS: Recently, we have shown that an algorithm that considers...

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Detalles Bibliográficos
Autores principales: Iglesias, Valentin, Conchillo-Sole, Oscar, Batlle, Cristina, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332698/
https://www.ncbi.nlm.nih.gov/pubmed/30642249
http://dx.doi.org/10.1186/s12859-019-2601-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332698/
https://www.ncbi.nlm.nih.gov/pubmed/30642249
http://dx.doi.org/10.1186/s12859-019-2601-3

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