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Struma Ovarii: A Report of Three Cases and Literature Review

Struma ovarii is a variant of mature cystic teratoma, with predominant thyroid element. Confirmatory diagnosis is by histopathology. It may mimic as ovarian malignancy in some. It may be associated with ascites in minority; even CA-125 has been found to be raised in some cases. We here report three...

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Autores principales: Singh, Pratibha, Lath, Nitisha, Shekhar, Shashank, Goyal, Manu, Gothwal, Meenakshi, Yadav, Garima, Khera, Pushpinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332726/
https://www.ncbi.nlm.nih.gov/pubmed/30692823
http://dx.doi.org/10.4103/jmh.JMH_53_18
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author Singh, Pratibha
Lath, Nitisha
Shekhar, Shashank
Goyal, Manu
Gothwal, Meenakshi
Yadav, Garima
Khera, Pushpinder
author_facet Singh, Pratibha
Lath, Nitisha
Shekhar, Shashank
Goyal, Manu
Gothwal, Meenakshi
Yadav, Garima
Khera, Pushpinder
author_sort Singh, Pratibha
collection PubMed
description Struma ovarii is a variant of mature cystic teratoma, with predominant thyroid element. Confirmatory diagnosis is by histopathology. It may mimic as ovarian malignancy in some. It may be associated with ascites in minority; even CA-125 has been found to be raised in some cases. We here report three cases – two operated for suspected ovarian malignancy in a postmenopausal female and one case operated for persistent benign ovarian cyst with raised CA-125 in a young female. In all histopathological diagnosis was a benign struma ovarii. It is difficult to diagnose these cases preoperatively as there are no specific clinical, radiological or serum markers for these rare tumors in the absence of thyroid biology abnormality. Most cases are diagnosed on histopathology. These benign tumors many times require extensive staging laparotomy for suspected ovarian malignancy in the absence of preoperative diagnosis. Prognosis is good for these tumors. Subtle radiological signs and a clinical suspicion can avoid extensive staging laprotomies in these patients.
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spelling pubmed-63327262019-01-28 Struma Ovarii: A Report of Three Cases and Literature Review Singh, Pratibha Lath, Nitisha Shekhar, Shashank Goyal, Manu Gothwal, Meenakshi Yadav, Garima Khera, Pushpinder J Midlife Health Case Series Struma ovarii is a variant of mature cystic teratoma, with predominant thyroid element. Confirmatory diagnosis is by histopathology. It may mimic as ovarian malignancy in some. It may be associated with ascites in minority; even CA-125 has been found to be raised in some cases. We here report three cases – two operated for suspected ovarian malignancy in a postmenopausal female and one case operated for persistent benign ovarian cyst with raised CA-125 in a young female. In all histopathological diagnosis was a benign struma ovarii. It is difficult to diagnose these cases preoperatively as there are no specific clinical, radiological or serum markers for these rare tumors in the absence of thyroid biology abnormality. Most cases are diagnosed on histopathology. These benign tumors many times require extensive staging laparotomy for suspected ovarian malignancy in the absence of preoperative diagnosis. Prognosis is good for these tumors. Subtle radiological signs and a clinical suspicion can avoid extensive staging laprotomies in these patients. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6332726/ /pubmed/30692823 http://dx.doi.org/10.4103/jmh.JMH_53_18 Text en Copyright: © 2018 Journal of Mid-life Health http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Series
Singh, Pratibha
Lath, Nitisha
Shekhar, Shashank
Goyal, Manu
Gothwal, Meenakshi
Yadav, Garima
Khera, Pushpinder
Struma Ovarii: A Report of Three Cases and Literature Review
title Struma Ovarii: A Report of Three Cases and Literature Review
title_full Struma Ovarii: A Report of Three Cases and Literature Review
title_fullStr Struma Ovarii: A Report of Three Cases and Literature Review
title_full_unstemmed Struma Ovarii: A Report of Three Cases and Literature Review
title_short Struma Ovarii: A Report of Three Cases and Literature Review
title_sort struma ovarii: a report of three cases and literature review
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332726/
https://www.ncbi.nlm.nih.gov/pubmed/30692823
http://dx.doi.org/10.4103/jmh.JMH_53_18
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