Malignant Mixed Mullerian Tumor Secondary to Tamoxifen for Ca Breast: Shadow of the Past!

Tamoxifen is used in the treatment of hormone-responsive breast cancer because of its antiestrogenic effect. However, it also has an estrogenic effect on the uterus, thereby increasing the risk of endometrial hyperplasia, endometrial polyp, and malignant mixed Mullerian tumor (MMMT). This case descr...

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Detalles Bibliográficos
Autores principales: Bisu, Surendra, Choudhary, Vinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332727/
https://www.ncbi.nlm.nih.gov/pubmed/30692818
http://dx.doi.org/10.4103/jmh.JMH_79_18
Descripción
Sumario:Tamoxifen is used in the treatment of hormone-responsive breast cancer because of its antiestrogenic effect. However, it also has an estrogenic effect on the uterus, thereby increasing the risk of endometrial hyperplasia, endometrial polyp, and malignant mixed Mullerian tumor (MMMT). This case describes the pathogenesis and risk of MMMT due to long-term tamoxifen intake in hormone-responsive breast cancer.

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