Therapy‐related acute myeloid leukemia after chemotherapy in extensive disease‐small cell lung cancer

We experienced therapy‐related acute myeloid leukemia (t‐AML) in a patient with extensive disease‐small cell lung cancer (ED‐SCLC). This case is rare and has educational message because ED‐SCLC has a poor prognosis and often cannot survive until developing therapy related hematological malignancy. F...

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Detalles Bibliográficos
Autores principales: Ueda, Naoko, Fujita, Kohei, Okuno, Yoshiaki, Nakatani, Koichi, Mio, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332741/
https://www.ncbi.nlm.nih.gov/pubmed/30656018
http://dx.doi.org/10.1002/ccr3.1931
Descripción
Sumario:We experienced therapy‐related acute myeloid leukemia (t‐AML) in a patient with extensive disease‐small cell lung cancer (ED‐SCLC). This case is rare and has educational message because ED‐SCLC has a poor prognosis and often cannot survive until developing therapy related hematological malignancy. Furthermore this case had unique chromosomal abnormalities. With recent advances in chemotherapy and radiotherapy, the prognosis of lung cancer has improved, while t‐AML has been increasing in frequency.

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