Tumor-derived extracellular vesicles inhibit osteogenesis and exacerbate myeloma bone disease

Background: As a hallmark driver of multiple myeloma (MM), MM bone disease (MBD) is unique in that it is characterized by severely impaired osteoblast activity resulting from blocked osteogenesis in bone marrow-derived mesenchymal stem cells (BM-MSCs). The mechanisms underlying this preferential blo...

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Detalles Bibliográficos
Autores principales: Zhang, Liming, Lei, Qian, Wang, Hongxiang, Xu, Cuiwei, Liu, Teng, Kong, Fancong, Yang, Cui, Yan, Guoxin, Sun, Li, Zhao, Aiqi, Chen, Wenlan, Hu, Yu, Xie, Hui, Cao, Yulin, Fu, Fenfen, Yuan, Guolin, Chen, Zhichao, Guo, An-Yuan, Li, Qiubai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332790/
https://www.ncbi.nlm.nih.gov/pubmed/30662562
http://dx.doi.org/10.7150/thno.27550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332790/
https://www.ncbi.nlm.nih.gov/pubmed/30662562
http://dx.doi.org/10.7150/thno.27550

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