Loss of ABAT-Mediated GABAergic System Promotes Basal-Like Breast Cancer Progression by Activating Ca(2+)-NFAT1 Axis

Basal-like breast cancer (BLBC) is the most aggressive subtype with a poor clinical outcome; however, the molecular mechanisms underlying aggressiveness in BLBC remain poorly understood. Methods: The effects of gamma-aminobutyrate aminotransferase (ABAT) on GABA receptors, Ca(2+)-NFAT1 axis, and can...

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Detalles Bibliográficos
Autores principales: Chen, Xingyu, Cao, Qianhua, Liao, Ruocen, Wu, Xuebiao, Xun, Shining, Huang, Jian, Dong, Chenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332792/
https://www.ncbi.nlm.nih.gov/pubmed/30662552
http://dx.doi.org/10.7150/thno.29407

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