Indoleamine 2,3-Dioxygenase-Dependent Neurotoxic Kynurenine Metabolism Contributes to Poststroke Depression Induced in Mice by Ischemic Stroke along with Spatial Restraint Stress

AIM: Poststroke depression (PSD), which occurs in approximately one-third of stroke survivors, is clinically important because of its association with slow functional recovery and increased mortality. In addition, the underlying pathophysiological mechanisms are still poorly understood. METHODS: We...

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Detalles Bibliográficos
Autores principales: Koo, Young Soo, Kim, Hyunha, Park, Jung Hwa, Kim, Min Jae, Shin, Yong-Il, Choi, Byung Tae, Lee, Seo-Yeon, Shin, Hwa Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332926/
https://www.ncbi.nlm.nih.gov/pubmed/30693061
http://dx.doi.org/10.1155/2018/2413841

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